MacPorts (DarwinPorts) is a package management system that simplifies the installation of software on the macOS and Darwin operating systems. Developed by The MacPorts Project
License: Open Source
Homebrew-Cask extends Homebrew and brings its elegance, simplicity, and speed to macOS applications and large binaries alike. It only takes 1 line in your shell to reach 3500 Casks maintained by 4568 contributors. brew cask install google-chrome. Developed by Paul Hinze
License: Open Source
MacPorts is more suitable for advanced users who prefer building applications from source and require extensive customization. In contrast, Homebrew Cask is designed for ease of use, focusing on the installation of macOS applications with a simple command-line interface.