OpenMPT is a versatile tracker suitable for modern music production with support for various audio formats and plugins, while FamiTracker is specialized for creating NES-style music, offering real-time playback and an intuitive interface.
OpenMPT
Pros:
Supports multiple audio formats
User-friendly interface
Extensive plugin support
VST integration
Advanced automation features
Cons:
Steeper learning curve for beginners
Limited to Windows and Linux
Can be resource-intensive
Not primarily designed for retro music
Some features may be overwhelming for casual users