Duplicati
Open Source
Duplicati is a backup tool, not a file sync tool.
Mozy
Freemium
Mozy is an online backup service for both Windows and macOS users.
ChronoSync
Commercial
ChronoSync is a macOS application for periodic backups, bootable drive clones and folder synchronizations.
Carbon Copy Cloner
Commercial
Carbon Copy Cloner makes drive backup straightforward and accessible, even if you're uncomfortable with performing this process.
SuperDuper!
Freemium
SuperDuper lets you quickly back up your files or your entire hard drive, with multiple options for compression and storage location.
Arq
Commercial
Arq is a backup software platform.
Compare Time Machine with alternatives
Compare Duplicati and Time Machine and decide which is most suitable for you.
Compare Carbon Copy Cloner and Time Machine and decide which is most suitable for you.
Compare SuperDuper! and Time Machine and decide which is most suitable for you.
Compare ChronoSync and Time Machine and decide which is most suitable for you.