Nylas Mail Alternatives for Mac OS X

Thunderbird is a free, open-source email client developed by the Mozilla Foundation, offering robust features for managing multiple email accounts, integrated chat, and RSS feeds. Known for its extensibility and focus on user privacy and security.

Microsoft Outlook is a comprehensive personal information manager designed for managing email, contacts, calendars, and tasks.

Apple Mail is the default email client for macOS, iOS, and watchOS, offering a seamless and integrated email experience across Apple devices with features like rich text editing, multiple account support, and robust organization tools.

Postbox is a powerful and customizable email client designed for professionals managing high volumes of email. It offers robust features for organizing, searching, and managing multiple accounts efficiently, enhancing productivity through a clean interface and advanced tools.

Zimbra Desktop provides a unified interface for managing multiple email accounts, calendars, tasks, and contacts offline. It supports various protocols like IMAP, POP, CalDAV, and CardDAV, offering a comprehensive personal information management solution.

KMail is a powerful and flexible email client tightly integrated with the Kontact personal information manager suite. Part of the KDE ecosystem, it offers robust features for managing your email, including strong encryption options, support for multiple protocols like IMAP, POP3, and Exchange, and seamless integration with other Kontact components like the calendar and address book.

Spark is a powerful and intelligent email client designed to enhance your productivity and streamline your inbox management. It offers a range of features like smart inbox organization, email scheduling, and integrations with popular services, making it a comprehensive solution for busy professionals and individuals alike.

Polymail is an advanced email client for macOS and iOS, built to enhance productivity for professionals using Gmail. It goes beyond basic email functions with robust features like email tracking, scheduling, and team collaboration tools, all wrapped in a sleek and intuitive interface.